J Bone Joint Infect 2017; 2(1):29-37. doi:10.7150/jbji.16067
Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections
Zentrum für Orthopädie und Unfallchirurgie, Klinikum Saarbrücken, Saarbrücken, Germany.
The use of antibiotic-loaded cement spacers is an established method in the management of periprosthetic hip and knee joint infections. Despite inconsistencies among published studies, data shows that infection control rates exceed 90% with two-stage exchange arthroplasty. The present work reviews the current literature about antibiotic-loaded cement spacers and concentrates on the indications for spacer implantation, spacer production details, antibiotic impregnation, pharmacokinetic properties, clinical success, mechanical complications, and systemic safety.
Keywords: hip spacer, knee spacer, hip infection, knee infection, antibiotic-loaded bone cement.
Anagnostakos K. Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections. J Bone Joint Infect 2017; 2(1):29-37. doi:10.7150/jbji.16067. Available from http://www.jbji.net/v02p0029.htm