J Bone Joint Infect 2017; 2(3):136-142. doi:10.7150/jbji.18408

Short Research Communication

Brucella melitensis prosthetic joint infection

Domenica Flury1, Henrik Behrend2, Parham Sendi3, Matthias von Kietzell1, Carol Strahm1✉

1. Department of Infectious Diseases, Cantonal Hospital of St. Gallen, St. Gallen;
2. Department of Orthopaedics and Traumatology, Cantonal Hospital of St. Gallen, St. Gallen;
3. Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland.


Periprosthetic joint infection (PJI) due to Brucella spp. is rare. We report a case in a 75-year-old man and review 29 additional cases identified in a literature search. The diagnosis of Brucella PJI is challenging, in particular in non-endemic countries. Serological tests prior to joint aspiration or surgical intervention are reasonable. Involvement of infection control and timely information to laboratory personnel is mandatory upon diagnosis. There is no uniform treatment concept, neither with respect to surgical intervention nor for the duration of antimicrobials. Most cases have a successful outcome, irrespective of surgical modality, and with an antimicrobial combination regimen for 12 or more weeks.

Keywords: Brucella, Periprosthetic joint infection

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How to cite this article:
Flury D, Behrend H, Sendi P, von Kietzell M, Strahm C. Brucella melitensis prosthetic joint infection. J Bone Joint Infect 2017; 2(3):136-142. doi:10.7150/jbji.18408. Available from http://www.jbji.net/v02p0136.htm