J Bone Jt Infect 2020; 5(2):96-100. doi:10.7150/jbji.43801

Case Report

Clostridium cadaveris Osteomyelitis: an Unusual Pathogen which Highlights the Importance of Deep Tissue Sampling in Chronic Osteomyelitis

Ruth Alexandra Corrigan1,2✉, Jose Lomas-Cabeza1, David Stubbs1, Martin McNally1

1. Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Windmill Road, Oxford, OX3 7HE, UK.
2. Nuffield Department of Clinical Laboratory Sciences, Radcliffe Department of Medicine, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK.

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Citation:
Corrigan RA, Lomas-Cabeza J, Stubbs D, McNally M. Clostridium cadaveris Osteomyelitis: an Unusual Pathogen which Highlights the Importance of Deep Tissue Sampling in Chronic Osteomyelitis. J Bone Jt Infect 2020; 5(2):96-100. doi:10.7150/jbji.43801. Available from http://www.jbji.net/v05p0096.htm

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Abstract

Clostridium cadaveris, named following its identification in human corpses, is an unusual pathogen. We report the first case of C. cadaveris osteomyelitis. This case highlights the importance of deep tissue sampling and appropriate culture to correctly identify causative pathogens and guide targeted antimicrobial therapy in difficult-to-treat infections like chronic osteomyelitis.

Keywords: Chronic osteomyelitis, intra-operative sampling, Clostridium cadaveris